İdrar kotinin ve kotinin/kreatinin oranının çevresel tütün dumanı maruziyetinin bir biyolojik belirteci olarak kullanımı

Purpose: Exposure to Environmental Tobacco Smoke (ETS) remains a worldwide public health problem. The purpose of this study was investigate the relationship between parents' smoking habits at home and children's exposure environmental tobacco smoke by measuring urinary cotinine levels urine cotinine/creatinine ratios in children.
 Materials Methods: This case-control typed analytical conducted with 357 children 0-18 age group. case group consisted 180 exposed cigarette smoke. As control group, it 177 healthy non-smoking their family. creatinine spot were analyzed both groups.
 Results: level found be statistically higher those whose parents smokers, female gender, fathers low educational level, 3 or fewer rooms house. ratio smokers (15.91 pg/mg (1.54-147.54) vs 7.90 (1.29-68.52)), gender (13.19 (1.79-115.07) 10.45 (1.29-147.54)). Urinary ETS affected 1042 times more than unexposed [OR:1042,462, 95% CI (139.821.839-7772.246)]. 
 Conclusion: In present study, not light these results, can used as biomarker evaluate children. Educating is essential raising awareness teaching right behaviors protect health, especially environment.